Controllable stereoselective synthesis of trisubstituted alkenes by a catalytic three-component reaction of terminal alkynes, benzylic alcohols, and simple arenes.
نویسندگان
چکیده
The acid-catalyzed three-component reaction of terminal alkynes, benzylic alcohols, and simple arenes provides convenient and atom-economic access to an array of both Z- and E-isomers of trisubstituted alkenes with excellent stereoselectivity by switching reaction temperature and acidic catalysts.
منابع مشابه
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 7 16 شماره
صفحات -
تاریخ انتشار 2009